Theramine Reviews


One bottle of Theramine will cost $49 while 2 bottles will cost $135 and but you will get two bottles for free. If you buy 3 bottles the price will come out to $180 and you will get 3 bottles for free.

Other products that are not opioid based may not be effective enough to handle really tough bodily pains. The product we will be outlining today is an effective way to treat pain without the use of opioids.

It’s called Theramine and instead of harsh, habit-forming opioids, it uses amino acids that get depleted with age and through the ravages of inflammation.

It is claimed that Theramine is an effective and healthy alternative to modern pain medications and that it can restore some of the proper functions of the nervous system that may have been damaged or compromised.

Theramine is a joint supplement that gets to the root of chronic pain instead of just putting a band-aid over it like other products. It may be a good way to deal with persistent bodily pains.

*All individuals are unique. Your results can and will vary.

When I saw a pain mgmt doctor for lower back pain, I told him I wanted to try whatever I could to not have to take NSAIDS or Opioids. He recommended Theramine and Magnesium. I am taking both and along with a Keto diet, am completely pain free.

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Most voted positive review

Lots of nerve damage from military surgeries/ fractured neck. Works like a charm. Was on oxycontin and percs for many years and this is way better. No side effects. Doesnt make you stupid or mess with constipation. It’s a little difficult to get through the insurance as the company that produces this stuff is not on big pharmas love list. I would recommend it to anyone anytime any where. VA is no.

Most voted negative review

no idea of what it is supposed to do.

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When I saw a pain mgmt doctor for lower back pain, I told him I wanted to try whatever I could to not have to take NSAIDS or Opioids. He recommended Theramine and Magnesium. I am taking both and along with a Keto diet, am completely pain free.

I’ve been on this for one month. It is amazing for inflammation. I have been able to back off my Rx pain meds. My pain doesn’t go to the bone. It is not nearly as deep. My hands and feet rarely swell IIke they use too. Give it some time. It can take up to 60 days for full benefit. It is worth the money if you are in as much pain as I am in everyday.

My experience was after one day. A strong desire to go to bed and hide. I take normal Pain meds and never take more than needed. As in trying to get high. I take them because I need them for back, neck, shoulder, hip. this med give me a high. Almost a paranoid feeling. I ve gone to the BR 3 times, which is a good thing, but not worth this weird feeling. Does your body adjust to this med. or, is it a hidden high. I do not like this feeling.

I took this drug at the recommendation of my PCP due to some low back pain that just wouldn’t go away. I have an incredibly sensitive stomach and IBSD. I didn’t suffer from any stomach pain or problems with my IBSD when I was taking this pill. Other than that I can’t see a noticeable difference in my pain. However, I’m told that you need to take it for a while to start seeing results. It’s a bit pricy and not easy to find. We had to order direct from the manufacturer in LA. I’ve been thro ugh my first bottle but don’t know if I would order again. Read More Read Less

Helps when my muscle pain is intolerable. Would take it regularly for arthritis if it didn’t aggravate my stomach and cause explosive diarrhea (need to eliminate the whey).

Dry mouth, upset stomach, jittery anxious and slight agitated feeling. Didn’t improve knee pain.

This drug seems to help with the inflammation and swelling. I have severe back injury that I have had every dig imaginable wirh little to no relief until I stared taking this pill which seemed to either help or helped the other drugs to work better. It is EXTREMELY expensive but no pricr tag is too high for even a little pa in relief

I have only taken Theramine for 2 days and it really makes my stomach hurt, and the stomach ache is really persistent. It also gives me a vague nervous, edgy feeling. I can also feel some good effects, I feel more vitality in my body, and can appreciate it once the nervous feeling wears off. My stomach hurts pretty bad now on day 2 so will not be taking this anymore. Have not felt any difference in pain levels but its only been 2 days. Even taking an antacid didnt not curb the aching stomach, so for me this nutrient/medication is not going to work. This is not normal for me at all for my stomach to ache like this. Hope it goes away soon! :/ Read More Read Less

The manufacturer does not offer free trials. However, the manufacturer will accept returns if authorized by their customer service.

How Does Theramine Work?

Theramine contains ingredients that work by hindering neurotransmission (brain signals). This product also claims to improve the level of GABA in the brain. A GABA is a chemical messenger that affects the central nervous system and produces a relaxing and protective effect on the brain. A low level of GABA makes it difficult for the body to relax.

This product also works by supplying the body with nutrients that improve the health of the nervous system. Nourishment for the nervous system is critical as it plays a role in pain response and detection.

Theramine is a proprietary prescription Medical Food which concurrently enhances several neurotransmitters that are involved in pain modulation and sensation by providing neurotransmitter precursors in the form of amino acids, (see attached Monograph for detailed discussion). Small trials have found Theramine effective in reducing and modifying pain without demonstrable side effects. Theramine simultaneously stimulates the production of the neurotransmitters serotonin, GABA, brain induced cortisol, nitric oxide, and glutamate.

A Double Blind Placebo Study to Determine the Effectiveness of Theramine on the Management of Chronic Back Pain

Condition or disease Intervention/treatment Phase
Chronic Low Back Pain Other: Theramine (A medical food) Drug: Theraprofen Drug: Ibuprofen Phase 4

The diagnosis and management of back pain is a challenge for both primary care physicians and specialists. Establishing an etiology can be difficult and often problematic, with treatment options capable of producing serious and potentially life threatening side effects. Treatments often exert a modest impact on the natural history of the condition. Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to treat chronic back pain. NSAIDs are only moderately effective in relieving pain. NSAIDs are the leading cause of drug-induced gastrointestinal bleeds, the most common cause of drug-induced morbidity and mortality particularly at high dose. They can also exacerbate hypertension, edema and produce nephrotoxicity. The effects are also dose dependent. Recent data indicates NSAIDs are a risk factor for myocardial infarction, particularly at high doses. Recent data also indicates NSAIDs disrupt collagen repair in injured tissue. Muscle relaxants and narcotic analgesics show limited efficacy and often produce sedation, constipation or inappropriate usage. Physical therapy and local modalities often are not satisfying, costly, and require considerable investment of patient time.

Neurotransmitter depletion has been demonstrated to contribute to chronic pain states. Increased nutrient requirements associated with pain syndromes and the consequent reduced production of neurotransmitters contribute to maladaptive pain responses. The ability to enhance neurotransmitter production associated with pain syndromes is limited by multiple factors, specifically unavailability of adequate essential amino acids in the diet and increased turnover rates of amino acids needed to produce neurotransmitters in pain syndromes. Other factors such as prolonged pharmaceutical use deplete the nerve cells of neurotransmitters. Attempts to modify brain neurochemistry have focused on single neurotransmitters such as serotonin or GABA. However, this approach fails to address the complexity and complementary influences of multiple neurotransmitters on patient perception of pain and suffering.

Theramine is a proprietary prescription Medical Food which concurrently enhances several neurotransmitters that are involved in pain modulation and sensation by providing neurotransmitter precursors in the form of amino acids, (see attached Monograph for detailed discussion). Small trials have found Theramine effective in reducing and modifying pain without demonstrable side effects. Theramine simultaneously stimulates the production of the neurotransmitters serotonin, GABA, brain induced cortisol, nitric oxide, and glutamate.

Resource links provided by the National Library of Medicine

Pain was assessed using the Roland-Morris Pain Scale (RMPS), Oswestry Disability Index (OST), and a Visual Analog Scale (VAS) at baseline and again at Day 28. On Days 7 and 14, VAS and patient breakthrough medication usage were evaluated. Patients randomized to the ibuprofen group were given 400 mg/day in the morning with a two-capsule dose of placebo (L-alanine) twice daily. In the Theramine group, subjects were given a two-capsule dose of Theramine twice daily and a single capsule of placebo in the morning. The group receiving combination therapy (Theramine and ibuprofen) received a two-capsule dose of Theramine twice daily and 400 mg of ibuprofen in the morning.

Theramine: a Safe Pharmacologic Alternative for Chronic Back Pain

LAS VEGAS, NV—Theramine, a prescription-only amino acid food product, may offer a safe alternative to traditional pharmaceutical products used to treat chronic back pain, according to a presentation at PAINWeek 2012. Theramine is prescribed for patients with chronic pain, fibromyalgia, neuropathic pain, and inflammatory pain who cannot use conventional diets or supplements. It had been shown in a previous double-blind clinical trial to be effective in the treatment of chronic low back pain when compared with naproxen, a nonsteroidal anti-inflammatory drug (NSAID).

Fred McCall-Perez, PhD, from Targeted Medical Pharma, Inc., in Los Angeles, and colleagues reported the results of the randomized, double-blind, placebo-controlled that examined if medical foods can offer an alternative therapeutic approach for back pain, with fewer side effects. In 127 patients, the efficacy of Theramine for chronic back pain was compared with low-dose ibuprofen, an NSAID. Patients were randomized to one of three treatment arms: low-dose ibuprofen (n=42), Theramine (n=42), or a combination of Theramine and ibuprofen (n=43) for 28 days. Eligible patients had back pain >6 weeks. Acetaminophen was given as rescue therapy for pain, at a dosage of 650 mg–1,000 mg every 4–6 hours, for a total daily dose <4g.

Pain was assessed using the Roland-Morris Pain Scale (RMPS), Oswestry Disability Index (OST), and a Visual Analog Scale (VAS) at baseline and again at Day 28. On Days 7 and 14, VAS and patient breakthrough medication usage were evaluated. Patients randomized to the ibuprofen group were given 400 mg/day in the morning with a two-capsule dose of placebo (L-alanine) twice daily. In the Theramine group, subjects were given a two-capsule dose of Theramine twice daily and a single capsule of placebo in the morning. The group receiving combination therapy (Theramine and ibuprofen) received a two-capsule dose of Theramine twice daily and 400 mg of ibuprofen in the morning.

On the RMPS, the percent change from Baseline to Day 28 was statistically significant (P<0.01), showing improved pain ratings for both the Theramine and the combined Theramine with ibuprofen groups compared with the ibuprofen alone group (0.73, -50.3, -63.1 respectively). On the OST, the percent change from Baseline to Day 28 was statistically significant (P<0.01) for both the comparison of Theramine and combined groups vs. the ibuprofen alone group (-4.5, -41.9, -62.2 respectively) and for the comparison of combined group vs. Theramine (P<0.05). For CRC and IL-6, the percent change for both the Theramine and combined groups showed statistically significant reductions (P<0.01) compared to the ibuprofen alone group. Dr. McCall-Perez pointed out that high sensitivity C-reactive protein and interleukin-6 levels in the ibuprofen group increased over baseline levels.

The results of laboratory blood tests confirmed that administration of Theramine resulted in an increase in blood concentrations of the amino acid precursors associated with neurotransmitters involved in the modulation of pain. Study investigators concluded that Theramine reduces inflammatory markers and may provide safer pharmacologic alternative to traditional pharmaceuticals prescribed in the management of chronic back pain.

Theramine is manufactured at a cGMP-certified facility in the United States. According to FDA standards, the product’s components have been investigated and are generally recognized as safe (GRAS). To assure its safety and efficacy, the product is subjected to FDA oversight and control.

What Do Customers Have to Say About Theramine?

According to Theramine Reviews, using the medication has some favorable effects. Independent reviews with unfavorable remarks, on the other hand, have been censored or concealed.

The “theramine drug” is a supplement that is designed to help people who suffer from chronic pain and inflammation. The product has been in use for more than 30 years, and it has been shown to be effective in treating conditions such as arthritis, fibromyalgia, and migraines.

Frequently Asked Questions

Is Theramine FDA approved?

A: Theramine is not FDA approved.

What is Theramine used for?

A: Theramine is used to treat peptic ulcers and GERD. It can also be given by mouth or injected into a vein or muscle, depending on the severity of your symptoms.


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