prox deep wrinkle reviews

prox deep wrinkle reviews

All told, Pro-X Deep Wrinkle Treatment has the better formula compared with Olay’s other products with retinol, but its price should give you pause. If retinol is what you’re after, keep in mind that RoC and Neutrogena have compelling options in that category for less money.

Pro-X Deep Wrinkle Treatment

You might think that this product is another of the spackle-type moisturizers that have been showing up at cosmetic counters with a thicker texture meant to temporarily fill in lines and minor wrinkles. It isn’t. Instead, this is akin to a lightweight moisturizer, which is being marketed as a specialty treatment by Olay.

This doesn’t contain a single ingredient that distinguishes it in any meaningful way from other Olay products, but it’s worth considering for its blend of cell-communicating ingredients and antioxidants, all in a silky, thin lotion texture that pairs well with other products. Olay’s packaging helps keep the vitamin A in this product stable, which is a very good thing. The form of retinol included is retinyl propionate, which also appears in Olay’s Age Defying line, though jar packaging prevails for most of that line, which makes those products useless.

All told, Pro-X Deep Wrinkle Treatment has the better formula compared with Olay’s other products with retinol, but its price should give you pause. If retinol is what you’re after, keep in mind that RoC and Neutrogena have compelling options in that category for less money.

  • Includes anti-aging superstar retinol.
  • Contains a high amount of skin-brightening and pore-refining niacinamide.
  • Includes barrier-strengthening peptides.
  • Packaged to protect its light- and air-sensitive ingredients.
  • Fragrance free.
  • None.

Pro-X Deep Wrinkle Treatment is designed and professionally tested for the deepest wrinkles. This Specialized Treatment penetrates deep into your skins surface, combating the appearance of wrinkles.

Olay At-A-Glance

Starting decades ago with the now-classic Oil of Olay, this brand now offers an extensive range of skin-care products sold at drugstores and mass-market stores. Today’s Olay lineup for those concerned about staving off the effects of aging skin is impressive, comprising their Regenerist, Pro X, and Total Effects lines. All of these (and several other Olay products) contain the B vitamin niacinamide. As you might expect, the claims made for it are inflated, but niacinamide is a very helpful ingredient for all skin types, capable of exerting multiple benefits.

In fact, perhaps the biggest complaint about Olay is that there are a number of repetitive formulas within and between the sub-brands make this line confusing and tricky to shop! Still, there is a lot to like about this drugstore stalwart, with its main drawback being a few formulas containing fragrance or other ingredients that have the potential to cause irritation.

For more information about Olay, owned by Procter & Gamble, call (800) 285-5170 or visit

About the Experts

The Beautypedia team consists of skin care and makeup experts personally trained by the original Cosmetics Cop and best-selling beauty author, Paula Begoun. We’re fascinated by skin care and makeup products and thrilled when they meet or exceed our expectations, but we’re also disappointed when they fail to perform as claimed, are wildly overpriced, or contain ingredients scientific research has proven can hurt skin.

Our mission has always been to help you find the best products for your skin, no matter your budget or preferences. Beautypedia’s thorough and insightful reviews cut through the hype and provide reliable recommendations for all ages, skin types, and skin tones.

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I have used this for a month now and have not seen much difference.

Prox deep wrinkle reviews

Love Just pure luxurious and youthful exuberance with use. This is so perfect for all skin care needs! The packaging is lovely and so is the container! It?s easy to use and you get real results! Highly recommend to anyone looking for glowing skin!

I felt visible difference just by first use and felt my skin was supple than usual. I love this product with how it helps to hydrate older skin

I have used this for a month now and have not seen much difference.

I love this product have been using it now for 1 month and have noticed a difference in my wrinkles especially in my forehead.

I am a 49 year old woman with very little sun damage to my skin. And the Olay Prox smoothing cream product has made a great noticeable improvements in my skin. It is somewhat over priced however, Olay Prox smoothing cream is very relevant to my concerns.

Suprisingly this product didn’t make me break out. I usually break out with 1-2 pimples from time to time, but didn’t really notice an increase in pimples while using this. It is great mosturizer. I don’t have wrinkles yet (I’m 27) but have been meaning to look into preventative anti-aging creams so I was happy to get this sample. So far I really like it.

I just started using Olay ProX cream at night about 10 days ago and so far, I really like it. I’ve had to make some changes to my nighttime routine but nothing too drastic. I have to make sure that I regularly (2x per week) exfoliate my face and that my skin is clean clean clean before putting the cream on at night. What I love about it is the texture, scent, absorbtion speed, and the results that I’m starting to see! I try not to have unrealistic expectations for anti-age products, but it’s nice to know that some actually deliver! Again, I’ve only been using it a short period of time, but my skin seems a lot smoother and even-colored and for the first time in a long time, I’ve found a night cream that isn’t so thick that it feels like a mask and causes some sort of break out. I give it an A- or B+!

This seems to really work.

I have been using the Olay ProX Wrinkle Smoothing Cream for almost four weeks. My skin took a couple of weeks to adjust to the cream. The first two weeks I had breakouts. I rarely breakout. When I do “breakout” I end up with one or two pimples at a time; with this cream I had six or more pimples at a time for the first two weeks (I ended up buying an astringent). Breakouts aside, I have noticed that the soft wrinkles (as opposed to deep wrinkles) on my forehead have almost disappeared. Also, I have noticed the my complexion has improved. I believe the cream works; however, breakout are a side affect. I would not recommend this to people who are prone to breakouts; for other people I would suggest using an astringent for as long as you use the cream. The cream itself feels thick and velvety on my face and takes a few minutes to be absorbed by my skin. Overall, I saw results with this cream, as far as smoothing out soft wrinkles goes. On a scale from 1-10, 1 being horrible and 10 being a great product, I give this product a 7. Now for the packaging. It’s nice and looks like something you would find in a department store. There lies the problem! I think the reason these creams are so expensive is because consumers have to pay not only for the product itself but also for the fancy packaging. The packaging would still be just as good without the outside glass that surronds it. Maybe Olay could cut the cost for consumers by sticking to simple packaging. It’s what’s inside that counts! I feel like I’ve been a little harsh in reviewing this product; however, I am a fan and believer in Olay products; they are one of the best skin care brands out there.

I didn’t find this lotion to be oily. It makes my face feel very soft. I can’t tell a huge difference with wrinkles being smoothed.

I love this product, I have been using olay products past 2 years when this came in to market I gave it a try as i have light wrinkle and tried a lot of products to hide them but none worked and finally i thought of giving this a try. Its not greasy or oily its very light and makes my skin glow its smooth and withing few weeks i could make a difference on my face the wrinkles are barely seen. My skin in sensitive and i guess olay products work really well on me. Now my skin is softer and smoother than before. I gifted this product to my mother and she loved it too. I love it and i would recommend everyone to use it. At least give it a try.

Love it

Oil of Olay ProX is great. It took care of my dry skin after just one use! It’s light and doesn’t seem to clog pores. I break out if I’m not careful, so I use a combination of Arbonne face wash & the Proactive system along with this Oil of Olay ProX. So far the combination seems to be working well. I have a hard time finding a good face moisturizer that doesn’t cause break outs, and this one definitely does not. You’re supposed to put it on your face and neck at night before bed and after a few weeks you think you’re face looks younger. I don’t quite have wrinkles yet, but I would like to do what ever I can to prevent them, or at least put them off for as long as possible! I feel like the Oil of Olay ProX will help with that. The only thing I don’t like about it is that it comes in a plastic jar rather than a tube or pump, so when I apply it I end up with some globbed below my finger nail from getting it out of the jar. Not really big as far as complaints go, but still annoying! Doesn’t Clog Pores My skin is definitely acne prone and this has not caused me to break out at all.

ProX Deep Wrinkle contains retinol, which is high in antioxidants. They can repair damage to the skin by killing damaging free radicals and lowering oxidative stress, as well as protecting it from environmental stressors like pollution. The product also contains anti-inflammatory benefits, which decrease swelling and redness on the skin.

  • You may have an allergic skin reaction to an ingredient.
  • This product is expensive for the size of the bottle.
  • It’s out of stock or discontinued on some sites.

The ProX Deep Wrinkle reviews were mostly from happy customers. The majority of users found this product effective at removing their wrinkles and fine lines, smoothing their skin, and getting rid of dryness. There were a small number of users who said this product made little difference in their wrinkles and other signs of age.

As we age the composition, texture and appearance of our skin changes. Signs of skin aging include wrinkles, fine lines, loss of moisture, uneven tone, and dull, tired-looking skin. There are countless anti-wrinkle creams on the market promising to make skin look and feel younger. Many anti-wrinkle creams promise everything short of a facelift or to provide the much sought after “fountain of youth”. In reality most are just moisturizers marketed as anti-aging products.

Below you’ll find some of the most effective wrinkle serum/cream formulations on the market today, in our opinion.

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Prox deep wrinkle reviews

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.

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Once inside the skin, it hydrates, but not from the outside – putting pure water on the skin (hello long baths!) is drying.

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.

  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis

An often used emollient with a light and silky feel. It's very mild to both skin and eyes and spreads nicely and easily. It's often used in sunscreens as it's also an excellent solvent for sunscreen agents.

Polyethylene is the most common plastic in the world. It is a super versatile polymer (molecule from repeated subunits) and when it comes to cosmetics, it is often referred to as microbeads. Well, it used to be referred to as microbeads, as it was banned in 2015 in the " Microbead-Free Waters Act" due to the small plastic spheres accumulating in the waters and looking like food to fish. Well done by Obama.

But being versatile means that polyethylene does not only come as scrub particles but also as a white wax. In its wax-form, it is still well, alive and pretty popular. It thickens up water-free formulas, increases hardness and raises the melting point of emulsions and water-less balms. It is particularly common in cleansing balms and stick-type makeup products due to its ability to add body, hardness and slip to these formulas.

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).

A handy multi-tasker, white to light yellowish oil-loving wax that works very well in oil-in-water emulsions. It makes your skin feel nice and smooth (emollient), stabilizes oil-water mixes and gives body to them.

Oh, and one more thing: it's a so-called fatty alcohol – the good, emollient type of alcohol that is non-drying and non-irritating. It is often mixed with fellow fatty alcohol, Cetyl Alcohol, and the mixture is called Cetearyl Alcohol in the ingredient list.

A white, waxy emollient that gives "body" to skincare formulas. Comes from coconut or palm kernel oil.

Retinyl Propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare". You can read the who's who here but the TL;DR version is that tretinoin is the queen herself (the FDA-proven anti-aging active molecule), retinol is like Prince William (two conversion steps needed to be active) and Retinyl Palmitate is like little Prince George (three conversion steps needed to be active).

Similar to Retinyl Palmitate, Retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together. This puts our molecule in the place of little Princess Charlotte on the family tree, quite far away from the throne. However, not all retinol ester molecules are made equal when it comes to being transformed and being effective on the skin.

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As Dr. Fulton (the scientist behind both Retin-A and RP) puts it in his patent paper, "Other esters of vitamin A obtained from, for example, palmitic acid and acetic acid do not have the therapeutic advantages found with vitamin A propionate . Presumably, the [Retinyl Palmitate] molecule is so large, it is not able to transdermally reach the necessary part of the skin for activity. Similarly, vitamin A acetate is too small molecularly and therefore easily recrystallizes from any solution. vitamin A propionate is the appropriate molecular weight and configuration to both remain in a stable solution and to be transdermally delivered to a site where it is active." So while the effectiveness of other retinol esters is highly questionable, Retinyl Propionate seems to be the most effective retinol ester molecule, and it "unexpectedly provides all the benefits of vitamin A acid but minimizes the negative side effects", at least according to Dr. Fulton, the inventor of the molecule.

We know what you are thinking! This sounds great and all, but what about some proof? Some backup data not from the inventor himself? We looked into it and found three studies working with Retinyl Propionate.

In a 2007 study by Dr. Draelos, she references a 12-week, double-blind, placebo-controlled clinical trial that compared the effectiveness of 0.15% retinol with 0.3% Retinyl Propionate. Both actives were effective in reducing the appearance of facial wrinkles and hyperpigmentation and the 0.3% RP worked a bit better.

Another research that was done by Procter & Gamble combined multiple anti-aging actives including niacinamide, peptides and 0.3% of Retinyl Propionate and they compared this regimen with a 0.02% tretinoin regimen. They found that the cosmetic regimen was tolerated better, worked faster and gave comparable results. All this sounds very promising for RP, however, it is hard to know how much the other actives contributed to the positive results.

Last, but not least there is a study from 1998 that tested a 0.15% Retinyl Propionate cream and after 24 weeks found no statistically significant difference between the effects of the retinyl propionate cream and the placebo preparation for any of the clinical parameters of skin photoaging. However, after 48 weeks, the 0.15% RP worked wonders for actinic keratoses, a rough, scaly patch caused by UV damage (its name contains actinic, but it is not acne, has nothing to do with it (!)).

So, it seems that the minimum effective dose of Retinyl Propionate is larger than 0.15% which is not surprising given that it has to do three conversion steps to reach the active form, retinoic acid. But 0.3% RP (or more, obvs) seems to be an effective dose, and even though the proof is not as solid as it is for retinol itself, if you are looking for a more gentle alternative, or if you are in the mood for experimentation, Retinyl Propionate looks like a noteworthy alternative and the most promising option among retinol esters.

Though its name does not reveal it, Carnosine is a peptide, a small, two amino acid (β-Ala-His) one. It is naturally present in high concentrations in muscle and brain tissues, but the one used in cosmetic products is biomimetic, meaning that it is synthetically produced in a lab to copy the natural thing.

A 2017 review paper on topical peptides writes about Carnosine that it is a "well-documented aqueous antioxidant with wound healing activity".

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Other than that we can write about manufacturer-done in-vitro (in the lab, not on real people) studies that show Carnosine to have anti-glycation properties. Glycation is the not-so-nice process that happens when we bombard our body with too much sugar that results in damaged body proteins and eventually in more wrinkles.

Also, a manufacturer done in vitro study shows that carnosine might have collagen-boosing magic power. However, the 2017 research paper also mentions that even though Carnosine is a small molecule, it is water soluble and does not penetrate the skin past the top layers so we have some doubt if the collagen-boosting works in real life. We could find one anti-aging study made on real people that mentions Carnosine, but it was combined with a bunch of other anti-aging actives so it is pretty much impossible to know what Carnosine did or did not.

One last thing to mention is that there is also a manufacturer done clinical study (done on real people) that shows carnosine being effective against the damages caused by infrared (IR) radiation. (source)

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.

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Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.

Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.

If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.

As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.

A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.

A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing).

A copolymer is a big molecule that consists not of one but of two repeating subunits. This particular copolymer is a handy helper ingredient to form nice gel textures.

It usually comes to the formula combined with emollients (such as C13-14 Isoparaffin, Isohexadecane, Isononyl Isononanoate or Squalane) and can be used as an emulsifier and/or thickener to produce milky gel emulsions with a soft and non-tacky skin feel.

A light, velvety, unique skin feel liquid that is a good solvent and also makes the skin feel nice and smooth (aka emollient). It's often used in makeup products mixed with silicones to give shine and slip to the product. It's also great for cleansing dirt and oil from the skin as well as for taking off make-up.

We don’t have description for this ingredient yet.

A controversial preservative that has formaldehyde-releasing properties. It works great against bacteria and also has mild fungicide abilities.

Cosmetic chemist, Colin wrote a great article about formaldehyde and DMDM Hydantoin. He writes that formaldehyde is the perfect example of "the dose makes the poison" principle. It's a natural stuff that can also be found in fresh fruits and vegetables, and eating it in tiny amounts is totally ok. However, in larger amounts (according to Wikipedia 30 mL of a solution containing 37% formaldehyde) it's deadly.

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The amount of formaldehyde used in cosmetics either neat or through formaldehyde-releasing preservatives is tiny. Probably that is why the Cosmetic Ingredient Review Broad concluded both in 1988 and in 2008 that DMDM Hydantoin is "safe as used in cosmetics".

However, Colins argues that in the case of formaldehyde-releasing preservatives, formaldehyde is released slowly and the skin has probably not evolved to deal with that. The lingering formaldehyde might be toxic to the Langerhans Cells that are important for the skin's defense system. Another potential issue is that formaldehyde-releasers might also release other things while reacting with amino acids in the skin that is probably the explanation why some people are not allergic to formaldehyde but are allergic to formaldehyde-releasing preservatives. These are all theories, far from proven facts, but we feel that there are some justified reasons why formaldehyde-releasing preservatives and Dmdm Hydantoin count as controversial.

All in all, it's up to you to decide if you wanna avoid this preservative group or not. If so, there are other, less risky and more skin-friendly options out there.

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together.

It's often paired with glyceryl stearate – the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

The number at the end refers to the oil-loving part and the bigger the number the more emulsifying power it has. 20 is a weak emulsifier, rather called solubilizer used commonly in toners while 60 and 80 are more common in serums and creams.

A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula.

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right.

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.

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BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.

Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.

It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.

There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.

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As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. Its strong point is being effective against yeasts and molds, and as a nice bonus seems to be non-comedogenic as well.

It is safe in concentrations of less than 0.1% but is acutely toxic when inhaled, so it's not the proper preservative choice for aerosol formulas like hairsprays. Used at 0.1%, Iodopropynyl Butylcarbamate has an extremely low rate of skin-irritation when applied directly for 24 hours (around 0.1% of 4,883 participants) and after 48 hours that figure was 0.5%, so it counts as mild and safe unless your skin is super-duper sensitive.

A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.

The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4.

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Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%).

There are also studies comparing Palmitoyl Pentapeptide-4 with anti-aging gold standard, retinol. One of them compared 3ppm Pal-KTTKS with 700 ppm (0.07%) retinol and found that they showed similar wrinkle improving ability with the peptide showing better skin tolerability.