Metacell Renewal B3 Reviews

Serum SkinCeuticals Metacell Renewal B3 is somewhat expensive, but in this very costly area of skincare, it’s not as much as many other brands like DRMTLGY, Genucel, and Miami MD. This product contains a quality collection of anti-aging ingredients, but they could have included other substances as well. There are other products which are richer for the same price.

SkinCeuticals Metacell Renewal B3 Serum Review – Does It Really Work?

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What’s In Skinceuticals Metacell Renewal B3?


Niacinamide, also called vitamin B3, is one of those multi-tasking ingredients that does absolutely everything:

  • It reduces hyperpigmentation by stopping melanin (the pigment that gives skin its colour) from reaching the surface of the skin.
  • It makes fine lines and wrinkles smaller.
  • It hydrates skin better than petrolatum, which is considered the gold standard of hydration by dermatologists.
  • It counteracts sallowness.
  • It soothes skin and helps treat rosacea.
  • It busts acne.

Best of all? Unlike other effective multi-staskers, such as retinol and vitamin C, niacinamide has no side effects. It’s so gentle, even those with sensitive skin can safely use it. Isn’t that awesome?

Skinceuticals Metacell Renewal B3 contains 5% Niacinamide. It may seem like nothing, but it’s a lot! Definitely more than enough to get the job done.


Silicones aren’t as bad as you think. They do a lot of good things in skincare:

  • Enhance texture: They allow the cream to glide on smoothly, without tugging or pulling.
  • Fill in fine lines and wrinkles: It’s a trick to make them look temporarily smaller.
  • Softens skin: It makes it feel silky soft to the touch.

They don’t even suffocate skin: silicones have a particular molecular structure made up of larger molecules with wider spaces between each molecule. They create a barrier that keeps moisture in but still allows skin to perspire.

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Let’s start with the basics. Glycerin is in pretty much ALL skincare products for a reason.

It’s a wonderful humectant: that’s a fancy way of saying it draws moisture from the air and locks it into your skin. Once there, this extra moisture softens, plumps, and brightens your skin.

That’s the base you want to build the rest of your skincare routine on.


What a mouthful, eh?

This stuff is simply a synthetic Tripeptide. According to the manufacturer, it does two things:

  • It boosts the synthesis of hyaluronic acid in the skin, keeping it plumper and hydrated for hours.
  • It improves the quality of collagen fibers to keep skin firmer for longer.

The catch? I couldn’t find any independent studies it works as claimed. That doesn’t mean it doesn’t. But, you know, it’s always wise to take manufacturer’s claims with a pinch of salt…

I haven’t bought this Renewal B3 Lotion in for about a year. I had a Facial done before moving to NC and I started using SkinCeuticals C E Ferulic (already on my 3rd bottle), and I began adding in this Renewal B3 lotion back into my Skincare routine again. and my face has been so smooth, bright and just feels great!

Reviews For SkinCeuticals Metacell Renewal B3 Lotion

I love Metacell Renewal B3 Lotion, my skin is getting better. I recommended it.

Anti aging

I just started using this serum along with A.G.E. Interrupter and can already see a difference in my skin

Go to morning moisturizer!

I continue to purchase this moisturizer in the AM – nice and light but it gets the job done! I’ve seen such a difference in my face ever since I started using SkinCeuticals – you won’t regret it.

Visible reduction in fine lines

I purchased this as recommended by my aesthetician, whom I trust impeccably. I’ve been using it for just a short while, but so far I feel that it is helping reduce my fine lines as well as adding firmness to my skin. As a bonus, I’ve been able to put my hyaluronic acid aside, because of the 15% non-occlusive glycerin attracting a hydration to my skin. I like to use this in the am, prior to my moisturizer, sunscreen and makeup.

SkinCeuticals Metacell Renewal B3 Lotion

I haven’t bought this Renewal B3 Lotion in for about a year. I had a Facial done before moving to NC and I started using SkinCeuticals C E Ferulic (already on my 3rd bottle), and I began adding in this Renewal B3 lotion back into my Skincare routine again. and my face has been so smooth, bright and just feels great!

Deeply moisturizing!

I use this lotion in the evening after the B5 Serum Gel and let me tell you: it IS good! SkinCeuticals claim that it reduces dark spots & evens skin tone: I’m not sure about that yet as I still have a least half of the bottle, but it’s definitely a good moisturizer! The texture is light so it’s not sticky or unctuous, and two pumps are more than enough for both your face and neck!

Metacell renewal

Wonder product makes my skin feel moisturized and very lightweight

A maybe

I have used this Metacell renewal b3 lotion and I can’t say a like them. I forgot my own moisture and I tried this product because my sister has been using them. It wasn’t something that I expected would be. So 3 stars it is and I had skin break out too. I won’t try it again.

Love it

My face is so smooth after I use this. I love it!


Works well in combination skin

Usage of product too short

I have use Metacell renewal B3 lotion for only a few days. In such a short time, I don’t feel I can adequately analyze the results. I am confident that it will a welcome to my collection of SkinCeuticals products since the products are wonderful so I rated it at a 4 star. Contact me at a later date.

Another wonderful product from SkinCeuticals

I have used this renewal cream since it first came out. I absolutely love the results.

Metacell Renewal B3 Cream

This Is a very nice absorbing cream. It feels nice on the skin and it soaks in instantly. I’ve only used it for a short time but I think this is going to be one that I use every day for a long time. My face is brighter which is what I was going for using this cream

My new favorite routine

I have tried B3 and impassed with results smooth my skin and even skintone that what I’m looking for and I will continue use it

Loving this!

I got a sample of this product with another order and loved it. I’ve since ordered a full size. It has a velvety texture that melts into your skin and leaves it a bit matte. It’s moisturizing, but not overly so. It has a pleasant eucalyptus fragrance and a little goes a long way. I use less than a pea sized pump and it covers my entire face and neck. I haven’t been using it long enough to notice major changes yet, but overall my skin is improving and looking brighter and clearer than it was previously.

Helped immensely with dark spots and uneven skin tone

Wow. I’m very rarely super impressed with many products because the magic pill does not seem to exist for aging, sun damaged skin. I put this mostly on my neck and a chest. I’ve had this about a month and surprisingly, I’ve seen a huge difference in my skin tone. I’m no longer a sun worshipper but living in a warm, climate with the sun shining has definitely taken its toll on my skin. Will definitely buy again.

First time user

Light and silky feel, helped reduce wrinkles and age spots are lighter.

Best moisturizer ever!

Meta cell renewal b3 is an amazing moisturizer! I find that it’s the only moisturizer I need even in the winter! And it keeps my skin texture and my pores looking and feeling great! It surpassed every other moisturizer!

First time use

So far I love this product. It goes on smooth and absorbs quickly, it doesn’t leave my face oily. It’s too soon to see results but I will be purchasing again.

Brighter skin

I ordered this because I received a sample and so far I’m loving it!! I have very sensitive skin (rosacea) and react to almost everything new I try. It’s been a few weeks now and my skin is brighter and smoother. I hope I can keep this on my “must have” list.

aqua / water / eau, glycerin, dimethicone, niacinamide, propanediol, dimethicone/peg-10/15 crosspolymer, methylsilanol/silicate crosspolymer, sodium chloride, polymethylsilsesquioxane, phenoxyethanol, microcrystalline cellulose, ci 77163 / bismuth oxychloride, chlorphenesin, caprylyl glycol, sodium citrate, ethylhexyl hydroxystearate, peg-10 dimethicone, disodium edta, cellulose gum, laminaria digitata extract, adenosine, citrus aurantium amara flower oil / bitter orange flower oil, melaleuca viridiflora leaf oil, tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate, linalool, cymbopogon flexuosus oil, citral, limonene, pelargonium graveolens flower oil

Metacell Renewal B3

Metacell Renewal B3

Metacell Renewal B3 utilizes a patent-pending aqueous emulsion to deliver a high concentration of 5% niacinamide (vitamin B3) combined with a firming tripeptide concentrate, and 15% pure glycerin to address early signs of photoaging. While signs of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, creating a prematurely-aged appearance. This comprehensive daily emulsion visibly improves these early signs of photoaging by increasing cell turnover to resurface skin, help reclarify and even skin tone, and improve the appearance of wrinkles and surface elasticity.

  • Promotes skin renewal by increasing cell turnover
  • Strengthens skin’s moisture barrier
  • Reduces the appearance of discoloration and blotchiness
  • Lightweight emulsion delivers intense hydration without a heavy or tacky feel
  • Helps improve the appearance of skin’s firmness

Skinceuticals US - How To Use

Twice daily, massage 1-2 pumps into a thin, even layer onto the entire face, neck, and chest.


While signs of photoaging appear at different intensities according to skin biology, lifestyle, geography, sun protection behavior, and skincare regimen, they have a multiplicative effect, resulting in a prematurely-aged appearance.

Niacinamide has been extensively studied for over 30 years within the dermatological and scientific community for its multi-factorial benefits on photoaging. Traditional delivery methods to optimize niacinamide on skin can disrupt the skin’s barrier and counteract the moisturizing and protective benefits. SkinCeuticals research labs have formulated a new delivery system to resolve this limitation. The non-disruptive delivery system of the formula architecture optimizes niacinamide delivery, while reinforcing the skin’s barrier. It is free of ingredients that traditionally occlude skin’s barrier, in order to allow niacinamide to be effective on skin.

  • 5% niacinamide (vitamin B3)
    Helps reduce the appearance of skin discoloration and strengthens skin’s moisture barrier
  • 2.5% firming tri-peptide concentrate
    A blend of powerful peptides helps reduce the look of fine lines, and improves the appearance of firmness
  • 15% pure glycerin
    This humectant has water-binding properties that deliver intense hydration without a heavy or tacky feel

In a 12-week clinical study, Metacell Renewal B3 showed significant improvement in signs of photoaging:

  • 15% improvement in the appearance of radiance and luminosity
  • 20.9% improvement in the appearance of fine lines
  • 10.9% improvement in the appearance of firmness


A dermatologist-controlled 12-week clinical on 56 female subjects, ages 40-55. Subjects applied Metacell Renewal B3 twice daily. Subjects also used SkinCeuticals Gentle Cleanser and Physical UV Defense SPF 30 as needed.

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