life extension cognitex elite reviews

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life extension cognitex elite reviews

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Study to Assess the Efficacy of Cognitex (Cognitex001)

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Condition or disease Intervention/treatment Phase
Elderly Memory Impairment Dietary Supplement: Cognitex Phase 4

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Layout table for study information

Study Type : Interventional (Clinical Trial)
Actual Enrollment : 30 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: A Single-Center, Open-label Study to Assess the Efficacy of Cognitex in Elderly Subjects With Memory Impairment
Study Start Date : August 2008
Actual Primary Completion Date : March 2009
Actual Study Completion Date : August 2009

Resource links provided by the National Library of Medicine
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  • Dietary Supplement: Cognitex

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    Improvement of Cognitive Performance (Change From Baseline in Neuropsychological Computerized Test) [ Time Frame: Base line and 12 weeks ]

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Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information

Ages Eligible for Study: 60 Years to 90 Years (Adult, Older Adult)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
  1. Ability to give written informed consent.
  2. Age: 90≥ years ≥60.
  3. Gender: male and female.
  4. Memory test performance within or below the mean established for adults in the computerized cognitive tool, with a maximum of four neuropsychological subtests scored 1.5 SD above the mean.
  5. Language: Subjects must be able to read, write and speak Hebrew.
  6. Ability to perform tests and interviews.
  1. Evidence of delirium, confusion, or other disturbances of consciousness.
  2. Evidence of dementia.
  3. Any Neurological disorder that could produce cognitive deterioration. Such disorders include Parkinson’s disease, stroke, intracranial hemorrhage, local brain lesions including tumors and normal pressure hydrocephalus.
  4. History of any infective or inflammatory brain disease including those of viral, fungal, or syphilitic etiologies.
  5. Head injury immediately preceding cognitive deterioration.
  6. Evidence of depression as determined by a the Geriatric Depression Scale (short version) score of 5 or more.
  7. Current diagnosis or history of alcoholism or drug dependence.
  8. Any medical disorder that could produce cognitive deterioration including renal, respiratory, cardiac, and hepatic disease, diabetes mellitus, endocrine, metabolic or hematological disturbances unless well controlled, and malignancy not in remission for more than two years
  9. Use of anti-clotting or antiplatelet medications or supplements for less than two years.
  10. History of clotting or platelet disorder unless well controlled.
  11. Use of any supplement that may significantly affect cognitive functioning during the month prior to study initiation.
  12. Use of any experimental medication within 1 month prior to screening or as concomitant medications.
  13. History of hypersensitivity or allergy to soy or fish.

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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Cognitex® Elite

Cognitex® Elite Benefits

  • Promotes healthy attention & focus
  • Encourages healthy mood & memory
  • Supports brain blood circulation & neurotransmitter levels
  • Offers potent neuroprotective benefits
  • Helps inhibit inflammation to promote brain health

The ashwagandha plant (Withania somnifera) is one of the most-studied Indian herbs. Clinical trials indicate that ashwagandha promotes both brain and mood health. It can increase stress resilience promoting calmness and making it easier to handle daily challenges. 11-13

The neurohormone pregnenolone modulates brain plasticity to help maintain healthy cognitive function, attention and memory performance, and mood

Whole-food wild blueberry complex

Blueberry phytonutrients can help inhibit age-related decline in cognitive and motor function. Our Cognitex® uses a whole-food complex of wild blueberry species from with powerful antioxidant properties.

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The healthy adult brain is commonly thought to contain as many as 100 billion nerve cells, and you can supercharge their performance with focused nutrition. Cognitex® Elite Pregnenolone provides a steady supply of these compounds to support brain health as you age.

SIBELIUS™: SAGE extract for attention and memory

Sage extract is known to promote healthy levels of the essential neurotransmitter acetylcholine and other neurochemicals needed for optimal brain function. It also supports mood and cognitive performance. 1,2 Our Cognitex® Elite formula uses SIBELIUS™ Sage, a novel type of sage extract, which has been clinically studied to encourage healthy brain and cognitive function.

In a randomized, placebo-controlled, double-blind clinical study, SIBELIUS™ Sage improved accuracy of attention, working memory, and recognition and recall. 3 SIBELIUS™ Sage has even been shown to enhance feelings of calmness and contentedness. 1

Phosphatidylserine supports optimal brain cell function

Phosphatidylserine , an essential component of healthy cell membranes, is critical to brain metabolism and function, and supports brain-cell-to-brain-cell communication. 4,5 It promotes healthy cognitive function, healthy memory, concentration, attention and more. 6-10

Ashwagandha for stress and mental performance

The ashwagandha plant (Withania somnifera) is one of the most-studied Indian herbs. Clinical trials indicate that ashwagandha promotes both brain and mood health. It can increase stress resilience promoting calmness and making it easier to handle daily challenges. 11-13

Ashwagandha has been clinically studied to encourage aspects of healthy memory, cognition and mental performance such as attention, executive function and information processing speed. 14,15

Maintain mental focus and boost mood with pregnenolone

The neurohormone pregnenolone helps to maintain healthy youthful cognitive function, attention and memory performance. 16-18 In fact, pregnenolone has even been thought of as a neurotransmitter. 17 It has also been shown to support healthy, positive mood. 19,20

One way pregnenolone may be able to accomplish all this is by encouraging something called synaptic plasticity which is a key characteristic of youthful brains and brain function. 17

Enhance brain function with Blueberry

Blueberry phytonutrients can help inhibit age-related decline in cognitive and motor function. 21,22 Wild blueberry extracts have been shown to inhibit oxidative and inflammatory factors in brain cells to support memory health. 23,24

Our formula uses a whole-food complex of various blueberry species with powerful antioxidant properties.

Vinpocetine for cognitive function

Several clinical trials have demonstrated that vinpocetine, an alkaloid derived from the periwinkle plant, can support healthy brain blood flow, memory, concentration and overall cognitive function. 25-28

Uridine-5′-Monophosphate supports healthy brain function

Pre-clinical studies have found that uridine-5’-monophosphate supports the essential neurotransmitters acetylcholine and dopamine and can encourage healthy learning and memory. 29-31

  1. Neuropsychopharmacology. 2006;31(4):845-52.
  2. Drugs in R&D. 2017;17(1):53-64.
  3. Psychopharmacology. 2008;198(1):127-39.
  4. Prog Lipid Res. 2014;56:1-18.
  5. Annual review of biophysics. 2010;39:407-27.
  6. Nutritional neuroscience. 2008;11(3):103-10.
  7. Neurobiol Aging. 1981;2(3):209-13.
  8. Aging (Milan, Italy). 1993;5(2):123-33.
  9. Neurology. 1991;41(5):644-9.
  10. Nutrition (Burbank, Los Angeles County, Calif.). 2015;31(6):781-6.
  11. JANA. 2008;11(1)
  12. Indian journal of psychological medicine. 2012;34(3):255-62.
  13. Journal of alternative and complementary medicine (New York, N.Y.). 2014;20(12):901-8.
  14. Pharmacognosy research. 2014;6(1):12-18.
  15. Journal of dietary supplements. 2017;14(6):599-612.
  16. J Steroid Biochem Mol Biol. 2016;160:78-87.
  17. Psychopharmacology. 2014;231(17):3537-56.
  18. Progress in neurobiology. 2003;71(1):43-8.
  19. Psychiatry research. 2010;178(2):309-12.
  20. Neuropsychopharmacology. 2014;39(12):2867-73.
  21. Ann N Y Acad Sci. 2007;1100:470-85.
  22. J Agric Food Chem. 2010;58(7):3996-4000.
  23. Behavioural brain research. 2009;198(2):352-8.
  24. Nutritional neuroscience. 2008;11(4):172-82.
  25. Annals of medical and health sciences research. 2014;4(4):654-61.
  26. Ideggyogyaszati szemle. 2007;60(7-8):301-10.
  27. International clinical psychopharmacology. 1991;6(1):31-43.
  28. Ideggyogyaszati szemle. 2012;65(3-4):115-20.
  29. Brain research. 2007;1133(1):42-8.
  30. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008;22(11):3938-46.
  31. Journal of molecular neuroscience : MN. 2005;27(1):137-45.

Supplement Facts

Serving Size 2 vegetarian tablets

Servings Per Container 30

SIBELIUS™: SAGE extract (leaf) [std. to 2.5% rosmarinic acid]

Proprietary Wildcrafted Blueberry Blend

Sensoril® ashwagandha extract (root, leaf) [std. to 10% withanolide glycoside conjugates]

Other ingredients: microcrystalline cellulose, stearic acid, calcium silicate, croscarmellose sodium, silica, aqueous film coating (hypromellose, glycerin, purified water), maltodextrin, vegetable stearate.

SIBELIUS is a trademark of Sibelius Limited.
CHRONOSCREEN is a trademark of Chronos Therapeutics Limited.
Sensoril® is protected under US patent Nos. 6,153,198 and 6,173,092 and is a registered trademark of Natreon, Inc.

  • Take two (2) tablets, preferably early in the day, or as recommended by a healthcare practitioner.

Do not use if you are of childbearing age, pregnant or planning to become pregnant.

  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

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If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

So, it’s recommended for the curious consumer to start with more basic, single ingredient choline supplementsthat can be purchased at a much lower price.

The idea behind Cognitex by LEF is to naturally enhance the biochemical mechanisms which already exist in the brain. When you find the right supplement for your personal goals, lifestyle, and body, the effects can be profound.

The original nootropic remedy, Piracetam (part of the racetam class), focuses its effects simply and powerfully upon the action of acetylcholine receptors. Without artificially spiking hormones, Piracetam increases the brain’s natural abilities.

Piracetam also facilitates communication between those structures once they are in place. The result is bright clear mental energy, fast and efficient thoughts, and sharper reasoning abilities. Memory is also improved.

By keeping neural tissue adaptable and healthy, supplements like the racetams provide powerful protection against degenerative diseases. For added benefit to mood and relief from depression symptoms, the similar supplement Aniracetam is often taken.

This compound is like a super-charged version of Piracetam with an addition mood lifting component, created by interaction with AMPA receptors. Either of these supplements can be paired with a circulation booster, like Vinpocetine mentioned above, for added efficacy.

Prices for these compounds tend to be as much as 5-6 times lower than for branded supplements like Cognitex. With a little bit of research, you can save money, and receive powerful brain boosting, age-protective benefits for a fraction of the price.

From the first year of life through school age, children who are short for their age (Stunted) or underweight for their age score lower than their normal-sized peers (On average) in cognitive and motor tasks and in school achievement. Necessarily, these approaches should be paralleled by research that aims to disentangle the effects of lifestyle habits at different points along the aging and disease continuum. In addition, immediate recall was more enhanced by whey peptide consumption than delayed recall, suggesting that whey peptide is associated with memory recall requiring attention. In theory, these could help, as vitamins and minerals have many functions in our central nervous systems which may help keep the brain healthy and our minds working well. Because the subgroup who had cognitive benefits could not be identified prior to vitamin c supplementation, these results have limited clinical applicability. However, other research suggests that ginkgo may not improve memory among people who are healthy. Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A systematic review (Pdf). Growing preclinical and clinical research in healthy individuals or at the early stage of cognitive decline has demonstrated the beneficial impact of nutrition on cognitive functions.

Life Extension Cognitive Memory Formulas

Therefore, our objective is to review current evidence on the efficacy and harm of the most commonly used dietary supplements for cognitive health. He also hopes that someday, the supplement industry will be more rigorously regulated. However, the team note a lack of certain nutrients, such as vitamins b9 and b12, appear to be linked to problems with cognitive function or brain health, and that supplements might prove useful in people with deficiencies. The research is clear: A whole-food, unprocessed diet that includes plenty of healthy fats is good for the brain. Three hypothetical scenarios in which the effects of undernutrition and a poor-quality environment may show additive or interacting effects on children’s motor, cognitive, and socioemotional development. Chronic malnutrition, as measured by physical growth that is far below average for a child’s age, is also associated with reduced cognitive and motor development. However, as with other brain health supplements, the science does not support the claims.

From the first year of life through school age, children who are short for their age (Stunted) or underweight for their age score lower than their normal-sized peers (On average) in cognitive and motor tasks and in school achievement. Necessarily, these approaches should be paralleled by research that aims to disentangle the effects of lifestyle habits at different points along the aging and disease continuum. In addition, immediate recall was more enhanced by whey peptide consumption than delayed recall, suggesting that whey peptide is associated with memory recall requiring attention. In theory, these could help, as vitamins and minerals have many functions in our central nervous systems which may help keep the brain healthy and our minds working well. Because the subgroup who had cognitive benefits could not be identified prior to vitamin c supplementation, these results have limited clinical applicability. However, other research suggests that ginkgo may not improve memory among people who are healthy. Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A systematic review (Pdf). Growing preclinical and clinical research in healthy individuals or at the early stage of cognitive decline has demonstrated the beneficial impact of nutrition on cognitive functions.

Of course, supplements are only one of several arms of the memory-enhancing industry. For example, a neuroimaging study demonstrated that the rear hippocampus, a part of the brain that underlies spatial memory, increased in volume as london taxi-driver trainees learned the layout of the city streets. These recommendations are very much in line with our seven steps for brain health. Indicating the relevance of gut microbiota for cognition, a first human study assessing cognitive tests and brain imaging could distinguish obese from nonobese individuals using a microbial profile 126, the authors found a specific microbiotic profile, particularly defined by actinobacteria phylum abundance, that was associated with microstructural properties in the hypothalamus and in the caudate nucleus. As mentioned above, you can benefit immensely from a proactive brain health plan that includes basic lifestyle advice coupled with vitamin deficiency prevention, and supplementation with vitamins that promote brain health. Some of the 50,000 different types of supplements out there claim to improve your mood, energy, vitamin levels and overall health. In a major study called mind, seniors who adopted such a diet and limited their salt intake had a 35 percent lower risk for cognitive decline as they aged, and strict adherence to the diet cut the risk by more than 50 percent.

They only suggested an apparent improvement in memory loss in institutionalized elderly people without ci or with mci if previously they were well nourished. Middle-age and older americans worried about losing their mental acuity are increasingly turning to loosely regulated dietary supplements. Here are more supplements doctors wish women would stop wasting money on. Fish oil supplementation increases event-related posterior cingulate activation in older adults with subjective memory impairment. Still, this does not mean that the brain supplements may not work, says dr. According to the world health organization (Who), there are 50 million people with dementia, with 10 million new cases each year. Available screening instruments are not fully appropriate for mci assessment because they do not allow a precise quantitative definition of domain-specific impairment, for example, in episodic memory, with reference to an age- and education-matched population.