bacomind bacopa extract reviews

At present, there are no known interactions between bacopa and foods, other herbs, or supplements.

What Is Bacopa?

Cathy Wong is a nutritionist and wellness expert. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health.

Arno Kroner, DAOM, LAc, is a board-certified acupuncturist, herbalist, and integrative medicine doctor practicing in Santa Monica, California.

Bacopa (Bacopa monniera) is an herb long used in Ayurveda—the traditional medicine of India. Bacopa is widely promoted as a treatment for memory disorders, anxiety, and thyroid health. However, not all of these benefits are supported by scientific evidence. Bacopa is also referred to as andri, Bacopa monnieri, herb of grace, herpestis herb, Herpestis monniera, Indian pennywort, and water hyssop.

If you're considering trying bacopa, make sure to consult your primary care provider first to weigh the pros and cons and discuss whether it's appropriate for you.

It should not be confused with gotu kola, an herb that also goes by one of bacopa's other names—brahmi.

Singh, R. H. and Singh, L. Studies on the Anti-Anxiety Effect of the Medhya Rasayana Drug, Brahmi (Bacopa monniera Wettst.) – Part I. Journal of Research in Ayurveda and Siddha 1980;1(1):133-148.

When taken by mouth: Bacopa is possibly safe when used in doses up to 600 mg daily for up to 12 weeks. Common side effects include stomachcramps, nausea, and dry mouth.

Pregnancy and breast-feeding: There isn’t enough reliable information to know if bacopa is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: Bacopa is possibly safe when taken by mouth by children 6-12 years old for up to 6 months.

Slow heart rate (bradycardia): Bacopa might slow down the heart rate. This could be a problem in people who already have a slow heart rate or other heart disease. If you have a heart condition, check with your healthcare provider before using bacopa.

Gastrointestinal tract blockage: Bacopa might make GI tract blockage worse. If you have a GI tract blockage, check with your healthcare provider before using bacopa.

Ulcers: Bacopa might make stomach ulcers worse. If you have stomach ulcers, check with your healthcare provider before using bacopa.

Lung conditions: Bacopa might make asthma or chronic obstructive pulmonary disease (COPD) worse. If you have asthma or COPD, check with your healthcare provider before using bacopa.

Thyroid disorders: Bacopa might increase levels of thyroid hormone. Bacopa should be used cautiously or avoided if you have a thyroid condition or take thyroid hormone medications.

Urinary tract blockage: Bacopa might make blockage of the urinary tract worse. If you have a urinary tract blockage, check with your healthcare provider before using bacopa.

It helps keep me stable mentally and actually more happy through the day. It helps me have regular Nevermind so that’s helps too! I love it

User Reviews for bacopa

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• Cognitive function (22 reviews)
• Other (6 reviews)
• Anxiety (5 reviews)
• General Health And Wellness (2 reviews)
• Attention deficit-hyperactivity disorder (ADHD) (2 reviews)

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Ease of Use

Satisfaction

Most voted positive review

Definite improvement in cognitive function, memory retention, processing complex info, faster flow of thoughts, great when writing essays, reports, analyzing data. Seems to work synergistically with caffeine but I am not advocating this. Has calming effect during stressful periods. Have been using for several years now and I’m not going back.

Most voted negative review

Only used it once. Be careful because it can lower blood pressure drastically. I took one pill (100 mg bacopa extract and 345 mg bacopa leaf in each) -Vitamin Shoppe brand. Ate no bkfst, just did my normal routine at the gym. I got dizzy during workout, nausea, blurred vision, almost passed out in gym restroom. Scary! Got workers to attend me and laid down. Felt like shock almost. Drank a.

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I took this for about 14 weeks and never got any improvement in memory, attention or depression in fact I felt worse on it and although that may be a coincidence I am certain it caused hyper thyroid for me (this is a risk for thyroid patients) also horrible diarrhea at the end and hair loss which could be related to high thyroid. Very disappointed that it didn’t help because I loathe taking drugs 🙁

It helps keep me stable mentally and actually more happy through the day. It helps me have regular Nevermind so that’s helps too! I love it

I have been taking Bacopa from Pure Mountain Botanicals at the suggestion of a friend. My attention, focus, memory have all improved. My only problem (and Im not sure it’s caused by Bacopa) is I have trouble sleeping. Anyone else??

I have been taking for over two years a health supplement with Bacopa extract as its main ingredient. I’ve noticed a considerable improvement in my short-term memory and ability to focus. It’s a lot easier to remember names and facts, and I don’t lose my train of thought in conversation any more. It’s easy to take–just two veggie capsules a day. I’d highly recommend it to anyone considering ways to improve short-term memory and focus.

The Web MD review is very behind the research. So much scientific research has been done in India, and India’s science is not fraud science, it’s the real thing. Why allopathic researchers claim “little scientific evidence,” in India there is vast amounts. I am 71 with hyper-thyroid issues, and bacopa does NOT speed them up further, every system is different. My brain was going haywire in the “keeping order” dept, and now my normal orderly functioning is back after one month of taking Bacopa. Th is helps my brain function better beyond belief! My processing speed and uptake is better than ever, and my memory is great now, and all was faltering badly. I am sleeping better, and anxiety and panic has subsided. I take bacopa with ashwagandha, shatavari and aloe vera. The Ayurvedic herbs from India are the best medicine there is! Few side effects and they WORK. Read More Read Less

Content

Who Is The Manufacturer Of Bacomind Bacopa Extract?

Double Wood Supplements have facilitated the formulation of the product. It is an online franchise that may deal with the production of a wide range of nootropics and other legal smart drugs. Despite lacking social media pages, they have received overall good reviews from users in their products.

Bacomind Bacopa Extract Review – Health Web Magazine Images

The field of herbal medicines and supplements is not as tightly regulated as the pharmaceutical industry. There are many claims made about B. monnieri such as its memory improving properties mostly based on the available pre-clinical data. This article aims to provide a detailed and up to date review of the neuroprotective and nootropic properties of B. monnieri, and its efficacy in the treatment of various diseases that have neurodegeneration as part of their pathology. Previous meta-analysis studies have reinvestigated all the diseases jointly and combined the effects on healthy people’s memory with that of people with memory complaints and other disorders. These studies could not give a clear picture of the efficacy of B. monnieri. We have, therefore, tried to separate the different diseases including the memory complaint groups, to provide more conclusive evidence of B. monnieri’s efficacy as a neuroprotective and nootropic drug.

Introduction

Neurological disorders include a wide array of problems including neuronal deterioration, cognitive decline, depression, anxiety and have been considered as one of the greatest risks to human health 1 . Even though older adults are more prone to the disease complications, studies reveal that the individual is affected even at a younger age but the pathological outcomes are shown at a later stage 2,3 . Traditional medicinal practices has a long history, and has been practiced worldwide for various diseases including neurological disorders. Due to advancement in scientific research, the role of medicinal plants in treating diseases, their adverse effects, and active compounds exerting the effects have been documented. However, most of the reports for the neuroprotective effects of herbs such as Bacopa monnieri (Linn.) Wettst. are from the pre-clinical studies, which makes it difficult to provide conclusive remarks. In this regard, the current article focusses on the meta-analysis of existing clinical studies on B. monnieri for its efficacy in treating neurological disorders that helps in connecting statistical significance and draw conclusions.

Bacopa monnieri and its active compounds

Bacopa monnieri, a plant belonging to the family Scrophulariaceae, commonly known as Brahmi, occurs naturally throughout south and Southeast Asia. It has a long history in traditional medicine and is known for its memory-enhancing properties as well as reducing anxiety 4 . The herb is currently marketed around the world as a memory enhancer and a blood sugar regulator. The plant has a vast number of active constituent compounds 5 including several alkaloids and saponins (Fig. 1), with the main active compounds being the steroidal saponins bacosides A (a mixture of bacoside A3, bacopaside II, bacopaside X, and bacopasaponin C) 6 . Though several other medicinal properties of the plant including cardioprotective, hepatoprotective and anticancer activities have been reported, B. monnieri has been widely used in Ayurveda majorly for its memory boosting property 7,8,9 .

Structures of bacoside compounds that can be isolated from B. monnieri.

Pre-clinical studies of B. monnieri in Alzheimer’s disease and neuroprotective properties

With the increase in life expectancy throughout the world, possibly due to better healthcare, and access to food and shelter, people are now living longer than any time in history 10 . However, with the increase in the average age of the world’s population, comes new challenges, one of which is neurodegenerative diseases 11 . Alzheimer’s disease is a neurodegenerative disease characterized by β-amyloid plaques, and brain atrophy 12 . The disease is chronic, and symptoms do not usually appear until a significant amount of damage has already occurred in the brain. 60% of dementia cases can be attributed to Alzheimer’s disease. Approximately 44 million people worldwide currently suffer with Alzheimer’s disease, and without the development of a cure or drugs effective at slowing the cognitive decline, this is expected to rise to 135 million by 2050. The cost of caring for patients with Alzheimer’s is equivalent to 1% of the world’s GDP, and then there is the emotional cost on those family members and caregivers who look after the patient as their cognitive ability slowly declines 13,14 .

Studies both in vitro and in vivo suggests the neuroprotective, and nootropic (smart drug) properties and the respective mechanism of action of B. monnieri against various neuronal insults. The hexane extract of B.monnieri prevented glutamate induced cell death in HT22 cells by alleviating oxidative and ER stress 15 , while the ethanol extract prevented β-amyloid induced toxicity in cultured neurons by inhibiting acetylcholinesterase enzyme and lipid peroxidation 6 . Studies in transgenic mice bearing human PS-1 and AβPP mutations have shown that both short and long-term treatment of B. monnieri reduces the amount of β-amyloid found in different regions of the brain 16 . The extract also diminished the neurodegenerative effects of ethylcholine aziridinium ion and colchicine in rats 17,18 , increased cerebral blood flow 19 and decreased the effects of stress in the brains of rats 20 . Many studies also indicate the antioxidant potential of B. monnieri that helps in mitigating the adverse effects of oxidative stress in neurons 6,17,18,21,22,23,24,25 . B. monnieri treatment of rats, under chronic unpredictable stress conditions, stimulates brain-derived neurotrophic factor (BDNF) and the receptor TrkB signaling pathway to activate cAMP response element-binding protein (CREB) resulting in neurogenesis and neuroprotection 26 . Further, the extract also inhibits the release of pro-inflammatory cytokines, namely Tumor necrosis factor-α (TNF-α) and Interleukin-6 (IL-6) from microglial cells and rat brains, thereby protecting from neuroinflammation, a pathological process occurring during neurodegeneration 27,28 . In addition, B. monnieri extract treatment also reversed aluminium chloride-induced anxiety and scopolamine induced learning and memory deficits in experimental animals 29,30 .

Even so, the neuroprotective and nootropic properties of B. monnieri and its efficacy in the clinical treatment of various diseases involving neurodegeneration as part of their pathology have not been fully evaluated. Most previous meta-analysis studies have combined the effects on healthy people’s memory with that of people with memory complaints and other disorders without concern for specific diseases 10 . Therefore, conclusive evidence for the clinical uses of B. monnieri as a neuroprotective, antidepressant or nootropic drug in different diseases is warranted for better understanding and more straightforward implementation in further studies.

Pre-clinical studies regarding depression

Major depression is a neurological condition that is characterized by a minimum of 2 weeks of low mood 31 . Anhedonia, the loss of interest in pleasurable activates, is often a symptom of major depression along with low self-esteem, lack of energy, and pain without any clear cause 31 . The main hypothesis for the cause of depression, is a lack of monoamines at the synapse in the brain. This is supported by the fact that nearly all antidepressant drugs work to increase the amount of monoamines available at the synapse either by blocking their reuptake, or preventing their break down 32 . At present the commonly prescribed anti-depressant drugs are only effective in 50% of patients, with partial effects seen in 80% of patients 32 . Thus, there is a need for new and improved anti-depressant drugs.

It is important to remember that there is no preclinical model that directly measures a drug’s effect on depression. There are in vivo behavioral animal models that have proved useful in predicting the anti-depressant effects of drugs; however, there is debate about true effectiveness of these models, and whether they are representative of antidepressant effects. One major problem with many of these models is that they are carried out in normal healthy animals, as there is no depressive phenotype model animal. There are protocols that induce depressive line behavior in some of the behavioral tests such as drug withdrawal 33,34 , and stress mechanisms such as chronic unpredictable stress (CUS) 35 . However, these models have been subject to criticism in terms of their reliability and repeatability 36,37,38,39 . The Porsolt forced swimming test or behavior despair test 40 is one of the most common behavioral tests used wherein, animals are subjected to two trials in a beaker of water from which they cannot escape, the first of which lasts 15 min, and the second 24 h later, and lasts five minutes. The time spent not moving except for small movements to stay above the water is measured in the second trial. There are also variations with just one trail 41 . Drugs that have been shown to improve symptoms of major depression, reduce the time spent immobile in this test has traditionally been correlated with improved mood. However, there is some debate about whether increased swimming is a learned behavior or an adaptation to its environment as it becomes more comfortable with its surroundings and less fearful 42 . Indeed, studies have shown that animals placed in a container of water from which they can escape, and thus experience no despair, also show less swimming in the second trial 43 . There are also other contradictions with these despair behavioral models, such as that drugs are administered acutely in these tests, whereas in clinical studies many days or weeks of treatment are required before any antidepressant effects are observed. The reason for this phenomenon is as yet unknown 44 . One possible explanation is the involvement of other receptors and pathways such as the sigma-1 receptor 45,46 , BDNF 47,48,49 , and inflammation related pathways 50,51 , which over chronic treatment periods increases the plasticity of the neurons and encourages neuron growth 52,53,54,55 .

Bacopa monnieri has been shown to have effects that mimic commonly prescribed antidepressants in the forced swim test (as well as other paradigms such as the tail suspension test and shuttle box testing) in mice and rats 26,56,57,58,59 . It is interesting that in one of these studies, using mice suffering from morphine withdrawal as a model of depression, the effect is only seen with chronic treatment 57 . Furthermore, using the CUS to model depression in rats, BDNF expression in the hippocampus of the rats was reduced, which is prevented by B. monnieri (80 mg/kg). Also, neurogenesis in the Rat hippocampus was improved (compared to the CUS) as measured by 5-bromo-2-deoxyuridine/neuronal nuclei, along with reduction in corticosterone levels 26 . In this study the effects of B. monieri mimic those of the positive control (imipramine 20 mg/kg) which acts primarily as a sigma-1 ligand 46,60 . Other studies have also shown that CUS induced reductions in BDNF, AKT and CREB expression are reversed by B. monnieri treatment 61,62 indicating sigma-1 receptor activation 63,64,65,66,67,68,69 which is hypothesized to be involved in the activities of antidepressant drugs 45,46 . However, there has not been a study directly investigating the role of the sigma-1 receptor in the antidepressant activities of B. monnieri, although it does seem to be a possible target.

Aims of this manuscript

The field of herbal medicines and supplements is not as tightly regulated as the pharmaceutical industry. There are many claims made about B. monnieri such as its memory improving properties mostly based on the available pre-clinical data. This article aims to provide a detailed and up to date review of the neuroprotective and nootropic properties of B. monnieri, and its efficacy in the treatment of various diseases that have neurodegeneration as part of their pathology. Previous meta-analysis studies have reinvestigated all the diseases jointly and combined the effects on healthy people’s memory with that of people with memory complaints and other disorders. These studies could not give a clear picture of the efficacy of B. monnieri. We have, therefore, tried to separate the different diseases including the memory complaint groups, to provide more conclusive evidence of B. monnieri’s efficacy as a neuroprotective and nootropic drug.

Bacomind is available through a number of channels, though it does take a bit of digging around to find it for sale. Ali Baba sells this product in powder form, between $25 and $80 a kilogram, depending on how much you order at a time. Pricing is dependent on the size of the order, as it’s generally sold in bulk.

Bacomind Review: Don’t Buy Before You Read This!

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What is it?

Bacomind is an enriched composition of the herbal ingredient bacopa monnieri, a plant with memory enhancing properties. Bacomind is used to help older adults maintain their memory and cognitive function, as well as children with learning disabilities.

Bacomind is a powder that can be mixed into various supplements or drinks to boost cognitive function over time. Bacomind has undergone extensive clinical testing and has been shown to revitalize the nerve cells in the brain.

Our reviewers have discovered that Memotenz is the secret to improving mental performance, naturally. Made from a blend of herbal ingredients, like St. John’s Wort, bacopa monnieri and others, this supplement improves learning, enhances focus and helps users experience a more reliable memory. For more information about how Memotenz can help you boost your brain power – click here.

Bacomind Ingredients and Side Effects

Bacomind is a single ingredient that can be used on its own, or as a component in other supplements. Here’s a look at bacopa monnieri and the benefits you can expect from using this ingredient:

Bacopa Monnieri

Bacopa Monnieri: A plant that grows year-round in India, bacopa monnieri has been used for centuries in Ayurvedic medicine and has been shown to improve memory, cognitive function and overall intelligence, due to its ability to boost the condition of the brain and nerve cells.

Bacomind has undergone a number of clinical studies, which have demonstrated its use in treating children with learning disabilities, as well as older people experiencing memory loss or symptoms of Alzheimer’s disease.

Bacomind Quality of Ingredients

There’s not much to the formula of Bacomind, but’s it’s clear this ingredient is a good solution for people looking to improve symptoms of conditions like ADHD, or perhaps slow down development of dementia symptoms.

While we quite like this ingredient, it’s unclear whether a formula containing one ingredient, no matter how good, is as effective as a more comprehensive supplement. For example, Bacomind is purely bacopa monnieri, and does not contain any additional ingredients.

But, according to the website, this product has undergone a significant amount of testing and clinical trials, so there is definitely science that supports its claims.

The Price and Quality of Bacomind

Bacomind is available through a number of channels, though it does take a bit of digging around to find it for sale. Ali Baba sells this product in powder form, between $25 and $80 a kilogram, depending on how much you order at a time. Pricing is dependent on the size of the order, as it’s generally sold in bulk.

Bacomind is also available through a number of smaller health-oriented online stores, though none with a very strong reputation. Look toward health and supplement stores to check out pricing on this. Additionally, Amazon carries a number of bacopa supplements made from bacopa monnieri extract, which is essentially the same thing.

Should you go the Amazon route, it’s a good idea to look at the percentage of saponins included in the extract – Bacomind generally has a 40-50% saponin content in each dose, as a reference point.

Business of Bacomind

Bacomind is made by Natural Remedies, an India-based company specializing in extracts and other raw materials. Their contact information is as follows:

Phone: +91 80 4020 9999

Address: Ashwathlakshmi Mansion

No. 364, II Floor

16th Main, 4th ‘T’ Block,

Jayanagar, Bangalore – 560 041. INDIA

The Bacomind targets an audience of raw materials buyers, people looking for extracts to add to food formulations, supplements and other consumer goods. For this reason the site is designed in straightforward manner, without any bells, whistles or calls to action.

While it’s not especially e-commerce friendly, the Bacomind product page provides a number of case studies performed on Bacomind, as well as dosing information, and a list of benefits users can expect from taking this daily. The website recommends taking the product for 12 weeks, meaning, users will need to exercise some patience after adding this to their supplement routine.

Bacomind is supposed to do—boost free testosterone, improve energy, stamina, and sexual function — but not really how it accomplishes those things.

Unfortunately, it takes a bit of research for regular users to buy this product. Orders are made by speaking to a sales person, so there’s a good chance they’re expecting some large orders, which may or may not come with some high shipping charges.

EDITOR’S TIP: For the best results, our experts recommend using brain enhancement supplements for at least 3 months. Save your money by buying a few bottles at once.

Customer Opinions of Bacomind

Bacomind has some pretty positive results. Many consumers have opted to take this in pill form, as it’s easier to track the amount in each dose – and it seems most people use about 200 mg to 400 mg on a regular basis. Here’s a look at what users had to say after giving Bacomind a try:

“This really helps increase cognitive function. It is worth noting you generally have to consumer bacopa for about 8-12 weeks before you see any major changes, but stick it out, it’s worth it.”

“I love this product, and have definitely seen some positive changes in the way I’m processing information. Occasionally, I get a headache, but my memory and focus are much better.”

“I’ve only been taking this product for a few weeks, but I’ve noticed my mental clarity is much improved. I’ll keep taking this – haven’t experienced any negative results so far.”

“Not feeling the results as advertised. I’ve heard that it can take a while to see any major changes, so I’ll give this a couple more weeks. I’m also not really sure how much I’m supposed to be taking each day.”

It seems that Bacomind hasn’t produced many negative effects in users, most of the complaints we saw about this supplement mentioned they didn’t quite see the results they thought they would be getting. A few user reviews mentioned being patient may pay off, as the results accumulate, meaning many people need to wait a couple months before seeing any notable changes in their memory or thought processing ability.

Overall, it seems Bacomind could be a good product for a number of people looking for more clarity, without the stimulant effects you’ll find in a number of products targeting cognitive function, productivity and focus. In general, users may want to read into dosing and the recommended amount of product needed for their specific age and body mass, as users buying Bacomind in powder form will need to measure amounts themselves.

How Does Bacomind Compare?

• Product Name
• User Rating
• Good Company Reputation
• Quality Ingredients
• Money Back Guarantee

• Memotenz
  (Editor’s Choice)
• 95/100

Conclusion – Does Bacomind Work?

After evaluating Bacomind, and it’s full range of benefits, its seems this product may be a good resource for people who are looking for a way to boost mental clarify and focus, without the stimulant effects you’ll find in other brain supplements or nootropics.

The Bacomind website doesn’t offer much from a consumer standpoint, as its geared for a wholesale audience, as well as product formulators, but it is a decent resource for people who want to learn a bit more about the ingredient want to know more about the safety and efficacy of bacopa monnieri extract.

In terms of purchasing, it may be a little tricky for a regular end consumer to buy Bacomind for their own personal use, but it’s definitely possible with a little digging around. Consumers may want to ask for a certificate of origin in case their concerned about fake product or product hailing from a pollution-heavy region. A good alternative to buying raw materials is to look for a bacopa supplement, which can easily be found on Amazon or anywhere else that sells supplements.

In general, it is hard for us to recommend a product that only contains one ingredient. The quality of Bacomind is easily traceable and we see no issues with the product. But, it may be worthwhile to look into purchasing an alternative featuring bacopa as one of the key ingredients, as opposed to being the only ingredient.

But in the end, it all depends on what specific function people are looking for in a brain supplement. Some people are looking for an increase in energy along with improved memory, others want clarity or the ability to hone their focus. Bacomind could very well be a good option for a number of people, but a more comprehensive formula could prove to be more useful, as well as cost effective for many potential consumers.

We’ve reviewed a wide range of supplements before learning that Memotenz can help users increase their capacity for new memories, as well as making sure they keep track of old ones. This supplement relies on a blend of key ingredients like gingko biloba, St. John’s Wort and more to deliver great benefits that carry through all aspects of daily life.

The makers of Memotenz follow strict quality assurance guidelines, ensuring they are making a safe and effective product. Click here for a closer look at how Memotenz can help you safely transform your work performance.